DNA Polymerase I (AA 610-690) 抗体
This 兔 多克隆 anti-not_set antibody specifically detects not_set in ELISA 和 WB. The antibody is reactive with 人 samples.
产品编号 ABIN7219268
发货至:
中国
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中国
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Quick Overview for DNA Polymerase I (AA 610-690) 抗体 (ABIN7219268)
抗原
DNA Polymerase I
适用
人
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
ELISA, Western Blotting (WB)
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抗原表位
- AA 610-690
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原理
- DNA pol ι Polyclonal Antibody
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特异性
- DNA pol ι Polyclonal Antibody detects endogenous levels of DNA pol ι protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human DNA pol ι at AA range: 610-690
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亚型
- IgG
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anti-DNA Polymerase I (C-Term) antibody
适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- DNA Polymerase I
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别名
- DNA pol ι
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背景
- Rabbit Anti-DNA pol ι Polyclonal Antibody,POLI, RAD30B, DNA polymerase iota, Eta2, RAD30 homolog B,POLI (Polymerase (DNA) Iota) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and Fanconi anemia pathway. GO annotations related to this gene include damaged DNA binding and DNA-directed DNA polymerase activity. An important paralog of this gene is POLH. rror-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunogobulin genes. Forms a Schiff base with 5-deoxyribose phosphate at abasic sites, but may not have lyase activity.,DNA polymerase iota
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分子量
- observerd band 85kDa
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基因ID
- 11201
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UniProt
- Q9UNA4
抗原
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