DUSL2 抗体 (AA 390-470)
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Quick Overview for DUSL2 抗体 (AA 390-470) (ABIN7223336)
抗原
See all DUSL2 (DUS2L) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 390-470
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原理
- Rabbit Anti-DUS2L Polyclonal Antibody
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特异性
- DUS2L Polyclonal Antibody detects endogenous levels of DUS2L protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the C-terminal region of human DUS2L at AA range: 390-470
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- DUSL2 (DUS2L) (Dihydrouridine Synthase 2-Like (DUS2L))
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别名
- DUS2L
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背景
- DUS2L, DUS2, tRNA-dihydrouridine(20) synthase [NAD(P)+]-like, Up-regulated in lung cancer protein 8, URLC8, tRNA-dihydrouridine synthase 2-like, hDUS2DUS2 (dihydrouridine synthase 2) encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. DUS2 has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for DUS2.
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分子量
- 55kD
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基因ID
- 54920
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UniProt
- Q9NX74
抗原
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