DPYSL2 抗体 (pSer522)
Our Local Distributor
北京 101111
Quick Overview for DPYSL2 抗体 (pSer522) (ABIN7220078)
抗原
See all DPYSL2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer522
-
原理
- CRMP-2 (phospho Ser522) Polyclonal Antibody
-
特异性
- Phospho-CRMP-2 (S522) Polyclonal Antibody detects endogenous levels of CRMP-2 protein only when phosphorylated at S522.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from human CRMP-2 Phospho-Ser522
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))
-
别名
- CRMP-2
-
背景
- Rabbit Anti-CRMP-2 (phospho Ser522) Polyclonal Antibody,DPYSL2, CRMP2, ULIP2, Dihydropyrimidinase-related protein 2, DRP-2, Collapsin response mediator protein 2, CRMP-2, N2A3, Unc-33-like phosphoprotein 2, ULIP-2,DPYSL2 encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. DPYSL2 has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,Dihydropyrimidinase-related protein 2
-
分子量
- observerd band 62kDa
-
基因ID
- 1808
-
UniProt
- Q16555
-
途径
- Regulation of Cell Size
抗原
-