AKR1C1 抗体 (AA 30-110)
Quick Overview for AKR1C1 抗体 (AA 30-110) (ABIN7219994)
抗原
See all AKR1C1 (DDH) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-110
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原理
- DD1 Polyclonal Antibody
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特异性
- DD1 Polyclonal Antibody detects endogenous levels of DD1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human DD1 at AA range: 30-110
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))
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别名
- DD1
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背景
- Rabbit Anti-DD1 Polyclonal Antibody,AKR1C1, DDH, DDH1, Aldo-keto reductase family 1 member C1, 20-alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, Chlordecone reductase homolog HAKRC, Dihydrodiol dehydrogenase 1/2, DD1/DD2, High-affinity hepatic bile acid-binding protein, HB,AKR1C1 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.,Aldo-keto reductase family 1 member C1
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分子量
- observerd band 37kDa
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基因ID
- 1645
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UniProt
- Q04828
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途径
- Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
抗原
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