RASD2 抗体 (AA 190-270)
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北京 101111
Quick Overview for RASD2 抗体 (AA 190-270) (ABIN7220746)
抗原
See all RASD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 190-270
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原理
- Rabbit Anti-Dexras2 Polyclonal Antibody
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特异性
- Dexras2 Polyclonal Antibody detects endogenous levels of Dexras2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the C-terminal region of human Dexras2 at AA range: 190-270
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亚型
- IgG
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anti-RASD Family, Member 2 (RASD2) (AA 1-266) antibody
RASD2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1C7 unconjugated
anti-RASD Family, Member 2 (RASD2) (AA 86-114) antibodyRASD2 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RASD Family, Member 2 (RASD2) (Internal Region) antibodyRASD2 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RASD Family, Member 2 (RASD2) (AA 1-266) antibodyRASD2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- RASD2 (RASD Family, Member 2 (RASD2))
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别名
- Dexras2
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背景
- RASD2, TEM2, GTP-binding protein Rhes, Ras homolog enriched in striatum, Tumor endothelial marker 2RASD2 belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The RASD family member 2 functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients.
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分子量
- 35kD
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基因ID
- 23551
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UniProt
- Q96D21
抗原
-
