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DPPA4 抗体

The 兔 多克隆 anti-DPPA4 antibody (ABIN7228284) specifically detects DPPA4 in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7228284
发货至: 中国
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Quick Overview for DPPA4 抗体 (ABIN7228284)

抗原

See all DPPA4 抗体
DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))

适用

人, 小鼠, 大鼠

宿主

  • 49
  • 7
  • 2

克隆类型

  • 54
  • 4
多克隆

标记

  • 29
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DPPA4 antibody is un-conjugated

应用范围

  • 31
  • 18
  • 13
  • 13
  • 10
  • 9
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA
  • 原理

    Rabbit Anti-DPPA4 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of DPPA4 protein

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human DPPA4 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))

    别名

    DPPA4

    背景

    Developmental pluripotency-associated protein 4DPPA4 encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18. but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of DPPA4 have been identified. Alternative splicing results in multiple transcript variants.

    分子量

    33kD

    基因ID

    55211

    UniProt

    Q7L190
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