Desmoglein 4 抗体
Our Local Distributor
北京 101111
Quick Overview for Desmoglein 4 抗体 (ABIN7228310)
抗原
See all Desmoglein 4 (DSG4) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Rabbit Anti-DSG4 Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of DSG4 protein
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from part region of human DSG4 protein
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- Desmoglein 4 (DSG4)
-
别名
- DSG4
-
背景
- Desmoglein-4, Cadherin family member 13DSG4 (Desmoglein 4) is a Protein Coding gene. Diseases associated with DSG4 include Hypotrichosis 6 and Monilethrix. Among its related pathways are Keratinization and Developmental Biology. DSG4 encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a transmembrane component of desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix, characterized by impaired hair growth.
-
分子量
- 114kD
-
基因ID
- 147409
-
UniProt
- Q86SJ6
抗原
-