Desmoglein 3 抗体
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北京 101111
Quick Overview for Desmoglein 3 抗体 (ABIN7228308)
抗原
See all Desmoglein 3 (DSG3) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- DSG3 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of DSG3 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human DSG3 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Desmoglein 3 (DSG3)
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别名
- DSG3
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背景
- Rabbit Anti-DSG3 Polyclonal Antibody,Desmoglein-3, 130 kDa pemphigus vulgaris antigen, PVA, Cadherin family member 6,DSG3 encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. DSG3 is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris.,DSG3
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分子量
- observerd band 109kDa
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基因ID
- 1830
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UniProt
- P32926
抗原
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