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Desmoglein 1 抗体 (AA 130-210)

This anti-Desmoglein 1 antibody is a 兔 多克隆 antibody detecting Desmoglein 1 in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7220092
发货至: 中国
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Quick Overview for Desmoglein 1 抗体 (AA 130-210) (ABIN7220092)

抗原

See all Desmoglein 1 (DSG1) 抗体
Desmoglein 1 (DSG1)

适用

  • 118
  • 33
  • 22
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 70
  • 49
  • 1

克隆类型

  • 65
  • 55
多克隆

标记

  • 49
  • 11
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This Desmoglein 1 antibody is un-conjugated

应用范围

  • 61
  • 50
  • 38
  • 23
  • 20
  • 15
  • 11
  • 6
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 130-210

    原理

    Dsg1 Polyclonal Antibody

    特异性

    Dsg1 Polyclonal Antibody detects endogenous levels of Dsg1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human Dsg1 at AA range: 130-210

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Desmoglein 1 (DSG1)

    别名

    Dsg1

    背景

    Rabbit Anti-Dsg1 Polyclonal Antibody,DSG1, CDHF4, Desmoglein-1, Cadherin family member 4, Desmosomal glycoprotein 1, DG1, DGI, Pemphigus foliaceus antigen,DSG1 encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. DSG1 is found in a cluster with other desmoglein family members on chromosome 18. The desmoglein 1 has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.,Desmoglein-1

    分子量

    observerd band 114kDa

    基因ID

    1828

    UniProt

    Q02413

    途径

    Cell-Cell Junction Organization
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