Desmocollin 3 抗体
Quick Overview for Desmocollin 3 抗体 (ABIN7228302)
抗原
See all Desmocollin 3 (DSC3) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- DSC3 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of DSC3 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human DSC3 protein
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亚型
- IgG
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anti-Desmocollin 3 (DSC3) (AA 712-896) antibody
DSC3 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Desmocollin 3 (DSC3) antibodyKO Validated DSC3 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 25GB2690 unconjugated Recombinant Antibody
anti-Desmocollin 3 (DSC3) (AA 585-684) antibodyDSC3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4D2 unconjugated
anti-Desmocollin 3 (DSC3) (AA 822-850) antibodyDSC3 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Desmocollin 3 (DSC3) (AA 585-684) antibodyDSC3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Desmocollin 3 (DSC3) (AA 144-193) antibodyDSC3 适用: 人, 小鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Desmocollin 3 (DSC3) (N-Term) antibodyDSC3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Desmocollin 3 (DSC3)
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别名
- DSC3
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背景
- Rabbit Anti-DSC3 Polyclonal Antibody,Desmocollin-3, Cadherin family member 3, Desmocollin-4, HT-CP,The protein encoded by DSC3 gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are a cause of hypotrichosis and recurrent skin vesicles disorder. The protein can act as an autoantigen in pemphigus diseases, and it is also considered to be a biomarker for some cancers. Alternative splicing of this gene results in multiple transcript variants.,DSC3
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分子量
- observerd band 98kDa
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基因ID
- 1825
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UniProt
- Q14574
抗原
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