DENND5A 抗体 (AA 650-730)
Quick Overview for DENND5A 抗体 (AA 650-730) (ABIN7228184)
抗原
See all DENND5A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 650-730
-
原理
- DEN5A Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of DEN5A protein
-
纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
-
免疫原
- Synthesized peptide derived from part region of human DEN5A protein at AA range: 650-730
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- DENND5A (DENN/MADD Domain Containing 5A (DENND5A))
-
别名
- DEN5A
-
背景
- Rabbit Anti-DEN5A Polyclonal Antibody,DENN domain-containing protein 5A, Rab6-interacting protein 1, Rab6IP1,DENND5A (DENN Domain Containing 5A) encodes a DENN-domain-containing protein that functions as a RAB-activating guanine nucleotide exchange factor (GEF). This protein catalyzes the conversion of GDP to GTP and thereby converts inactive GDP-bound Rab proteins into their active GTP-bound form. The encoded protein is recruited by RAB6 onto Golgi membranes and is therefore referred to as RAB6-interacting protein 1. This protein binds with RAB39 as well. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Mutations in DENND5A are associated with early infantile epileptic encephalopathy-49.,DEN5A
-
分子量
- observerd band 141kDa
-
基因ID
- 23258
-
UniProt
- Q6IQ26
抗原
-