DEFa3 抗体 (Internal Region)
Quick Overview for DEFa3 抗体 (Internal Region) (ABIN7220016)
抗原
See all DEFa3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- Defensin α3 Polyclonal Antibody
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特异性
- Defensin α3 Polyclonal Antibody detects endogenous levels of Defensin α3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Defensin alpha3
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- DEFa3 (Defensin, alpha 3, Neutrophil-Specific (DEFa3))
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别名
- Defensin alpha3
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背景
- Rabbit Anti-Defensin α3 Polyclonal Antibody,DEFA3, DEF3, Neutrophil defensin 3, Defensin, alpha 3, HNP-3, HP-3, HP3,Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Neutrophil defensin 3 encoded by DEFA3, defensin, alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. DEFA3 differs from defensin, alpha 1 by only one amino acid. This gene and the gene encoding defensin, alpha 1 are both subject to copy number variation.,Neutrophil defensin 3
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基因ID
- 1668
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UniProt
- P59666
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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