DOCK11 抗体
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北京 101111
Quick Overview for DOCK11 抗体 (ABIN7228270)
抗原
See all DOCK11 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-DOC11 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of DOC11 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human DOC11 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- DOCK11 (Dedicator of Cytokinesis 11 (DOCK11))
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别名
- DOC11
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背景
- Dedicator of cytokinesis protein 11, Dedicator of cytokinesis protein 11, ACG, Zizimin-2DOCK11 (Dedicator Of Cytokinesis 11) is a Protein Coding gene. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and G-protein signaling_Regulation of CDC42 activity. Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Required for marginal zone (MZ) B-cell development, is associated with early bone marrow B-cell development, MZ B-cell formation, MZ B-cell number and marginal metallophilic macrophages morphology. Facilitates filopodia formation through the activation of CDC42.
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分子量
- 228kD
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基因ID
- 139818
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UniProt
- Q5JSL3
抗原
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