CRTAM 抗体 (AA 260-340)
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Quick Overview for CRTAM 抗体 (AA 260-340) (ABIN7228068)
抗原
See all CRTAM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 260-340
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原理
- Rabbit Anti-CRTAM Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of CRTAM protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human CRTAM protein at AA range: 260-340
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- CRTAM (Cytotoxic and Regulatory T Cell Molecule (CRTAM))
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别名
- CRTAM
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背景
- Class-I MHC-restricted T-cell-associated molecule, CD_antigen: CD355CRTAM (Cytotoxic And Regulatory T-Cell Molecule) is a Protein Coding gene. Among its related pathways are Class I MHC mediated antigen processing and presentation and Innate Immune System. GO annotations related to this gene include receptor binding. An important paralog of this gene is CADM1. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.
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分子量
- 43kD
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基因ID
- 56253
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UniProt
- O95727
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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