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CYFIP1 抗体 (AA 980-1060)

This anti-CYFIP1 antibody is a 兔 多克隆 antibody detecting CYFIP1 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7228120
发货至: 中国

Quick Overview for CYFIP1 抗体 (AA 980-1060) (ABIN7228120)

抗原

See all CYFIP1 抗体
CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

适用

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宿主

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克隆类型

  • 22
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多克隆

标记

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This CYFIP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 980-1060

    原理

    CYFP1 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of CYFP1 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human CYFP1 protein at AA range: 980-1060

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

    别名

    CYFP1

    背景

    Rabbit Anti-CYFP1 Polyclonal Antibody,Cytoplasmic FMR1-interacting protein 1 ,Specifically Rac1-associated protein 1, Sra-1,CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1) encodes a protein that regulates cytoskeletal dynamics and protein translation. The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization. This protein also interacts with the Fragile X mental retardation protein (FMRP) and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including CYFIP1 is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of CYFIP1 has been observed in various human cancers and the encoded protein may inhibit tumor invasion. CYFIP1 is a Protein Coding gene. Diseases associated with CYFIP1 include Fragile X Syndrome and Schizophrenia. Among its related pathways are RET signaling and Regulation of actin dynamics for phagocytic cup formation.,CYFP1

    分子量

    observerd band 137kDa

    基因ID

    23191

    UniProt

    Q7L576
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