COX10 抗体 (Internal Region)
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Quick Overview for COX10 抗体 (Internal Region) (ABIN7219600)
抗原
See all COX10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- COX10 Polyclonal Antibody
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特异性
- COX10 Polyclonal Antibody detects endogenous levels of COX10 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human COX10
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亚型
- IgG
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anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 1-160) antibody
COX10 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 383-410), (C-Term) antibodyCOX10 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24307 unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (Middle Region) antibodyCOX10 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 386-414), (C-Term) antibodyCOX10 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) antibodyCOX10 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 215-264) antibodyCOX10 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬, 斑马鱼, Bat, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 1-443) antibodyCOX10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 1-443) antibodyCOX10 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 180-229) antibodyCOX10 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, Bat, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))
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别名
- COX10
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背景
- Rabbit Anti-COX10 Polyclonal Antibody,COX10, Protoheme IX farnesyltransferase, mitochondrial, Heme O synthase,Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. COX10 encodes heme A: farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. COX10, heme A: farnesyltransferase cytochrome c oxidase assembly factor is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion.,Protoheme IX farnesyltransferase mitochondrial
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分子量
- observerd band 49kDa
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基因ID
- 1352
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UniProt
- Q12887
抗原
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