CYB561D1 抗体 (AA 160-240)
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北京 101111
Quick Overview for CYB561D1 抗体 (AA 160-240) (ABIN7221226)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 160-240
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原理
- CYB561D1 Polyclonal Antibody
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特异性
- CYB561D1 Polyclonal Antibody detects endogenous levels of CYB561D1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human CYB561D1 at AA range: 160-240
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亚型
- IgG
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anti-Cytochrome B-561 Domain Containing 1 (CYB561D1) (C-Term) antibody
CYB561D1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-561 Domain Containing 1 (CYB561D1) (AA 200-229), (C-Term) antibodyCYB561D1 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB28497 unconjugated
anti-Cytochrome B-561 Domain Containing 1 (CYB561D1) (AA 200-229), (C-Term) antibodyCYB561D1 适用: 人, 小鼠 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-561 Domain Containing 1 (CYB561D1) (C-Term) antibodyCYB561D1 适用: 人, 小鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CYB561D1 (Cytochrome B-561 Domain Containing 1 (CYB561D1))
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别名
- CYB561D1
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背景
- Rabbit Anti-CYB561D1 Polyclonal Antibody,CYB561D1, Cytochrome b561 domain-containing protein 1,CYB561D2 (Cytochrome b561 domain-containing protein 2), also known as putative tumor suppressor protein 101F6, is a 222 amino acid highly hydrophobic protein that contains six membrane spanning domains. Localized to endosomes and endoplasmic reticulum of the perinuclear region, CYB561D2 contains 2 heme-binding sites, through which it reduces ferric ions. CYB561D2 is ubiquitously expressed, with highest levels in lung, liver and kidney. Though expression of CYB561D2 is abundant in normal lung bronchial epithileal cells, CYB561D2 is absent in most lung cancers. The gene encoding CYB561D2 maps to human chromosome 3p21.3, a region that is prone to genetic alterations and is associated with frequent and early allele loss in many human cancers. Exogenous expression of CYB561D2 leads to the induction of caspase-independent apoptotic and autophagic pathways, resulting in the synergistic killing of tumor cells. This suggests an important role for CYB561D2 as a therapeutic intervention in cancer treatment.,Cytochrome b561 domain-containing protein 1
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分子量
- observerd band 23kDa
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基因ID
- 284613
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UniProt
- Q8N8Q1
抗原
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