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CSTB 抗体 (AA 20-60)

This 兔 多克隆 anti-CSTB antibody specifically detects CSTB in ELISA 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7228134
发货至: 中国
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Quick Overview for CSTB 抗体 (AA 20-60) (ABIN7228134)

抗原

See all CSTB 抗体
CSTB (Cystatin B (Stefin B) (CSTB))

适用

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宿主

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克隆类型

  • 89
  • 40
多克隆

标记

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This CSTB antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 22
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    AA 20-60

    原理

    Cystatin B Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of Cystatin B

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human Cystatin B protein at AA range: 20-60

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    CSTB (Cystatin B (Stefin B) (CSTB))

    别名

    Cystatin B

    背景

    Rabbit Anti-Cystatin B Polyclonal Antibody,Cystatin-B, CPI-B, Liver thiol proteinase inhibitor, Stefin-B,The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). One type of mutation responsible for EPM1 is the expansion in the promoter region of this gene of a CCCCGCCCCGCG repeat from 2-3 copies to 30-78 copies.,Cystatin B

    基因ID

    1476

    UniProt

    P04080

    途径

    Response to Water Deprivation
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