Cyclin T1 抗体 (AA 220-300)
Our Local Distributor
北京 101111
Quick Overview for Cyclin T1 抗体 (AA 220-300) (ABIN7227666)
抗原
See all Cyclin T1 (CCNT1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 220-300
-
原理
- Rabbit Anti-CCNT1 Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of CCNT1 protein
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from part region of human CCNT1 protein at AA range: 220-300
-
亚型
- IgG
-
-
anti-Cyclin T1 (CCNT1) (AA 375-410), (Middle Region) antibody
CCNT1 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IF, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin T1 (CCNT1) (AA 253-281) antibodyCCNT1 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB19562 unconjugated
anti-Cyclin T1 (CCNT1) antibodyKD Validated CCNT1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB150 unconjugated Recombinant Antibody
anti-Cyclin T1 (CCNT1) (AA 256-285), (Middle Region) antibodyCCNT1 适用: 人, 小鼠 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin T1 (CCNT1) (N-Term) antibodyCCNT1 适用: 人, 小鼠, 大鼠, Cow, 犬, 山羊, 马, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Cyclin T1 (CCNT1) (AA 1-726) antibodyCCNT1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cyclin T1 (CCNT1) (AA 325-375) antibodyCCNT1 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin T1 (CCNT1) (AA 425-475) antibodyCCNT1 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin T1 (CCNT1) (N-Term) antibodyCCNT1 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 非洲爪蟾, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Cyclin T1 (CCNT1) (Internal Region) antibodyVerified CCNT1 适用: 人 ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- Cyclin T1 (CCNT1)
-
别名
- CCNT1
-
背景
- Cyclin-T1, CycT1, Cyclin-TCCNT1 (Cyclin T1) encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of CCNT1 is implicated in tumor growth. Alternative splicing results in multiple transcript variants.
-
分子量
- 79kD
-
基因ID
- 904
-
UniProt
- O60563
抗原
-
