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Cyclin T1 抗体 (AA 220-300)

This 兔 多克隆 antibody specifically detects Cyclin T1 in WB 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN7227666
发货至: 中国
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Quick Overview for Cyclin T1 抗体 (AA 220-300) (ABIN7227666)

抗原

See all Cyclin T1 (CCNT1) 抗体
Cyclin T1 (CCNT1)

适用

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宿主

  • 47
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  • 1

克隆类型

  • 40
  • 12
多克隆

标记

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This Cyclin T1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 220-300

    原理

    CCNT1 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of CCNT1 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human CCNT1 protein at AA range: 220-300

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Cyclin T1 (CCNT1)

    别名

    CCNT1

    背景

    Rabbit Anti-CCNT1 Polyclonal Antibody,Cyclin-T1, CycT1, Cyclin-T,CCNT1 (Cyclin T1) encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of CCNT1 is implicated in tumor growth. Alternative splicing results in multiple transcript variants.,CCNT1

    分子量

    observerd band 79kDa

    基因ID

    904

    UniProt

    O60563
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