Cullin 7 抗体 (AA 1570-1650)
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北京 101111
Quick Overview for Cullin 7 抗体 (AA 1570-1650) (ABIN7228102)
抗原
See all Cullin 7 (CUL7) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1570-1650
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原理
- Rabbit Anti-CUL7 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of CUL7 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human CUL7 protein at AA range: 1570-1650
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- Cullin 7 (CUL7)
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别名
- CUL7
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背景
- Cullin-7, CUL-7The protein encoded by CUL7 (Cullin 7) is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in CUL7 are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for CUL7. CUL7 is a Protein Coding gene. Diseases associated with CUL7 include 3-M Syndrome 1 and 3-M Syndrome, Cul7-Related. Among its related pathways are Class I MHC mediated antigen processing and presentation and Unfolded Protein Response (UPR).
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分子量
- 186kD
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基因ID
- 9820
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UniProt
- Q14999
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途径
- ER-Nucleus Signaling
抗原
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