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COX-1 抗体 (AA 520-600)

The 兔 多克隆 anti-COX-1 antibody is suitable to detect COX-1 in samples from 人. It has been validated for WB, ELISA 和 IHC (p).
产品编号 ABIN7214300
发货至: 中国
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Quick Overview for COX-1 抗体 (AA 520-600) (ABIN7214300)

抗原

COX-1

适用

  • 4
  • 3
  • 2

宿主

  • 8

克隆类型

  • 8
多克隆

标记

  • 8
This COX-1 antibody is un-conjugated

应用范围

  • 8
  • 6
  • 6
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 2
    • 1
    • 1
    • 1
    AA 520-600

    原理

    Cox-1 Polyclonal Antibody

    特异性

    Cox-1 Polyclonal Antibody detects endogenous levels of Cox-1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the C-terminal region of human Cox-1 at AA range: 520-600

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    COX-1

    背景

    Rabbit Anti-Cox-1 Polyclonal Antibody,PTGS1, COX1, Prostaglandin G/H synthase 1, Cyclooxygenase-1, COX-1, Prostaglandin H2 synthase 1, PGH synthase 1, PGHS-1, PHS 1, Prostaglandin-endoperoxide synthase 1,PTGS1 is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. Prostaglandin-endoperoxide synthase 1 regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, prostaglandin-endoperoxide synthase 1 has been identified as a moonlighting protein. Prostaglandin-endoperoxide synthase 1 may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.,Prostaglandin G

    分子量

    observerd band 70kDa

    基因ID

    5742

    UniProt

    P23219
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