CIRBP 抗体
Our Local Distributor
北京 101111
Quick Overview for CIRBP 抗体 (ABIN7227910)
抗原
See all CIRBP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Rabbit Anti-CIRBP Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of CIRBP protein
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from part region of human CIRBP protein
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- CIRBP (Cold Inducible RNA Binding Protein (CIRBP))
-
别名
- CIRBP
-
背景
- Cold-inducible RNA-binding protein, A18 hnRNP, Glycine-rich RNA-binding protein CIRPCIRBP (Cold Inducible RNA Binding Protein) is a Protein Coding gene. Diseases associated with CIRBP include Cryptorchidism. Among its related pathways are DNA Damage and Translational Control. Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3-untranslated regions (3-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.
-
分子量
- 18kD
-
基因ID
- 1153
-
UniProt
- Q14011
-
途径
- Ribonucleoprotein Complex Subunit Organization
抗原
-