Cofilin 抗体 (pSer3)
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Quick Overview for Cofilin 抗体 (pSer3) (ABIN7221928)
抗原
See all Cofilin (CFL1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer3
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原理
- Cofilin (phospho Ser3) Polyclonal Antibody
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特异性
- Phospho-Cofilin (S3) Polyclonal Antibody detects endogenous levels of Cofilin protein only when phosphorylated at S3.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Cofilin Phospho-Ser3
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亚型
- IgG
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anti-Cofilin 1 (CFL1) (AA 1-166) antibody
CFL1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-Cofilin 1 (CFL1) antibodyKO Validated CFL1 适用: 人 WB, IF, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (AA 3-161) antibodyCFL1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (pSer3) antibodyCFL1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (AA 1-100) antibodyCFL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (AA 2-166) antibodyCFL1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, IF, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (AA 70-98) antibodyCFL1 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB23947 unconjugated
anti-Cofilin 1 (CFL1) (AA 4-144) antibodyCFL1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (pSer3) antibodyCFL1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (AA 1-166) antibodyCFL1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal AT1C1 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Cofilin (CFL1) (Cofilin 1 (CFL1))
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别名
- Cofilin
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背景
- Rabbit Anti-Cofilin (phospho Ser3) Polyclonal Antibody,CFL1, CFL, Cofilin-1, 18 kDa phosphoprotein, p18, Cofilin, non-muscle isoform,Cofilin is ubiquitously expressed in eukaryotic cells where it binds to actin, thereby regulating the rapid cycling of actin assembly and disassembly essential for cellular viability. Cofilin is a low molecular weight protein that binds to filamentous (F) actin by bridging two longitudinally associated actin subunits changing the F-actin filament twist. This process is allowed by the dephosphorylation of cofilin ser-3 by factors such as opsonized zymosan. Lim kinase 1, a serine kinase, phosphorylates cofilin and renders it unable to bind and depolymerise F-actin.,Cofilin-1
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分子量
- observerd band 19kDa
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基因ID
- 3716
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UniProt
- P23528
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途径
- Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
抗原
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