Factor VIII 抗体 (AA 2130-2210)
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Quick Overview for Factor VIII 抗体 (AA 2130-2210) (ABIN7214840)
抗原
See all Factor VIII (F8) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2130-2210
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原理
- Factor VIII Polyclonal Antibody
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特异性
- Factor VIII Polyclonal Antibody detects endogenous levels of Factor VIII protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human Factor VIII at AA range: 2130-2210
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亚型
- IgG
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anti-Coagulation Factor VIII (F8) (AA 2253-2346) antibody
F8 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 1887-2044) antibodyF8 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 1854-1988) antibodyF8 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 1451-1550) antibodyF8 适用: 人, 小鼠 ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 85-190) antibodyF8 适用: 人, 小鼠, 大鼠 ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 401-500) antibodyF8 适用: 人, 小鼠, 大鼠, 兔 ELISA, ICC, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 1-216) antibodyF8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 213-312) antibodyF8 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 1E8 unconjugated
anti-Coagulation Factor VIII (F8) (AA 1264-1278), (Middle Region) antibodyF8 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VIII (F8) (AA 399-730) antibodyF8 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Factor VIII (F8) (Coagulation Factor VIII (F8))
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别名
- Factor VIII
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背景
- Rabbit Anti-Factor VIII Polyclonal Antibody,F8, F8C, Coagulation factor VIII, Antihemophilic factor, AHF, Procoagulant component,F8 encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. F8 produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. DefectsF8 results in hemophilia A, a common recessive X-linked coagulation disorder.,Coagulation factor VIII
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分子量
- observerd band 300kDa
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基因ID
- 2157
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UniProt
- P00451
抗原
-
