Coagulation Factor IX 抗体 (AA 412-461)
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Quick Overview for Coagulation Factor IX 抗体 (AA 412-461) (ABIN7226924)
抗原
See all Coagulation Factor IX (F9) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 412-461
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原理
- Factor IX Polyclonal Antibody
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特异性
- Factor IX Polyclonal Antibody detects endogenous levels of Factor IX.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from Factor IX at AA range: 412-461
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Coagulation Factor IX (F9)
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别名
- Factor IX
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背景
- Rabbit Anti-Factor IX Polyclonal Antibody,Coagulation factor IX, Christmas factor, Plasma thromboplastin component, PTC,F9(coagulation factor IX) encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of F9, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.,Factor IX
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分子量
- observerd band 52kDa
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基因ID
- 2158
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UniProt
- P00740
抗原
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