Claudin 6 抗体 (pTyr219)
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北京 101111
Quick Overview for Claudin 6 抗体 (pTyr219) (ABIN7225802)
抗原
See all Claudin 6 (CLDN6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr219
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原理
- Claudin-6 (phospho Tyr219) Polyclonal Antibody
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特异性
- Phospho-Claudin-6 (Y219) Polyclonal Antibody detects endogenous levels of Claudin-6 protein only when phosphorylated at Y219.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Claudin-6 Phospho-Tyr219
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Claudin 6 (CLDN6)
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别名
- Claudin-6
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背景
- Rabbit Anti-Claudin-6 (phospho Tyr219) Polyclonal Antibody,CLDN6, Claudin-6, Skullin,Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. CLDN6 (claudin 6) encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. CLDN6 methylation may be involved in esophageal tumorigenesis. CLDN6 is adjacent to another family member CLDN9 on chromosome 16.,Claudin-6
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分子量
- observerd band 23kDa
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基因ID
- 9074
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UniProt
- P56747
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途径
- Hepatitis C
抗原
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