Claudin 19 抗体 (AA 50-130)
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Quick Overview for Claudin 19 抗体 (AA 50-130) (ABIN7214214)
抗原
See all Claudin 19 (CLDN19) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-130
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原理
- Claudin-19 Polyclonal Antibody
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特异性
- Claudin-19 Polyclonal Antibody detects endogenous levels of Claudin-19 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Claudin-19 at AA range: 50-130
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Claudin 19 (CLDN19)
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别名
- Claudin-19
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背景
- Rabbit Anti-Claudin-19 Polyclonal Antibody,CLDN19, Claudin-19,The product of CLDN19 belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in CLDN19 are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for CLDN19.,Claudin-19
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分子量
- observerd band 23kDa
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基因ID
- 149461
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UniProt
- Q8N6F1
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途径
- Cell-Cell Junction Organization, Hepatitis C
抗原
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