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Claudin 11 抗体 (AA 130-210)

This 兔 多克隆 anti-Claudin 11 antibody specifically detects Claudin 11 in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7222878
发货至: 中国
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Quick Overview for Claudin 11 抗体 (AA 130-210) (ABIN7222878)

抗原

See all Claudin 11 (CLDN11) 抗体
Claudin 11 (CLDN11)

适用

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  • 1
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人, 小鼠, 大鼠

宿主

  • 51

克隆类型

  • 40
  • 11
多克隆

标记

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  • 3
  • 2
  • 2
  • 1
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  • 1
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This Claudin 11 antibody is un-conjugated

应用范围

  • 45
  • 16
  • 13
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  • 10
  • 5
  • 4
  • 3
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  • 1
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Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 8
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 130-210

    原理

    Claudin-11 Polyclonal Antibody

    特异性

    Claudin-11 Polyclonal Antibody detects endogenous levels of Claudin-11 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the C-terminal region of human Claudin-11 at AA range: 130-210

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Claudin 11 (CLDN11)

    别名

    Claudin-11

    背景

    Rabbit Anti-Claudin-11 Polyclonal Antibody,CLDN11, OSP, OTM, Claudin-11, Oligodendrocyte-specific protein,CLDN11 encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by CLDN11 is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein claudin 11 is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.,Claudin-11

    分子量

    observerd band 20kDa

    基因ID

    5010

    UniProt

    O75508

    途径

    Hepatitis C
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