CNTF Receptor alpha 抗体
Our Local Distributor
北京 101111
Quick Overview for CNTF Receptor alpha 抗体 (ABIN7227986)
抗原
See all CNTF Receptor alpha (CNTFR) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Rabbit Anti-CNTFR Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of CNTFR protein
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from part region of human CNTFR protein
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))
-
别名
- CNTFR
-
背景
- Ciliary neurotrophic factor receptor subunit alpha, CNTF receptor subunit alpha, CNTFR-alphaCNTFR encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in CNTFR may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for CNTFR.
-
分子量
- 40kD
-
基因ID
- 1271
-
UniProt
- P26992
-
途径
- JAK/STAT Signaling, Feeding Behaviour
抗原
-