C9orf89 抗体 (AA 40-120)
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北京 101111
Quick Overview for C9orf89 抗体 (AA 40-120) (ABIN7225394)
抗原
See all C9orf89 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-120
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原理
- BinCARD Polyclonal Antibody
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特异性
- BinCARD Polyclonal Antibody detects endogenous levels of BinCARD protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human BinCARD at AA range: 40-120
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亚型
- IgG
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anti-Chromosome 9 Open Reading Frame 89 (C9orf89) (AA 1-183) antibody
C9orf89 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 9 Open Reading Frame 89 (C9orf89) antibodyC9orf89 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 9 Open Reading Frame 89 (C9orf89) (AA 1-183) antibodyC9orf89 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- C9orf89 (Chromosome 9 Open Reading Frame 89 (C9orf89))
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别名
- BinCARD
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背景
- Rabbit Anti-BinCARD Polyclonal Antibody,C9orf89, Bcl10-interacting CARD protein, BinCARD,BinCARD (Bcl10-interacting CARD protein) is a 228 amino acid protein that exists as two alternatively spiced isoforms. BinCARD localizes to nucleus and is expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart, liver, thymus and brain. Containing a CARD domain, BinCARD plays a role in inhibiting the effects of Bcl10-induced activation of NFκB possibly by inhibiting the phosphorylation of Bcl10 in a CARD-dependent manner. The BinCARD gene maps to chromosome 9q22.1. Chromosome 9 consists of about 145 million bases and 4 % of the human genome and encodes nearly 900 genes. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKAP.,Bcl10-interacting CARD protein
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基因ID
- 84270
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UniProt
- Q96LW7
抗原
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