CDYL2 抗体 (AA 1-80)
Quick Overview for CDYL2 抗体 (AA 1-80) (ABIN7214140)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-80
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原理
- CDYL2 Polyclonal Antibody
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特异性
- CDYL2 Polyclonal Antibody detects endogenous levels of CDYL2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human CDYL2 at AA range: 1-80
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ICC (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CDYL2 (Chromodomain Protein, Y-Like 2 (CDYL2))
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别名
- CDYL2
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背景
- Rabbit Anti-CDYL2 Polyclonal Antibody,CDYL2, Chromodomain Y-like protein 2, CDY-like 2,CDY, a gene family expressed exclusively in the testis, localizes to a region of the Y chromosome frequently deleted in infertile males. CDY protein contains two functional domains, an N-terminal chromodomain, possibly functioning in heterochromatin interactions, and also a C-terminal domain which resembles enoyl-CoA-isomerase, a protein involved in fatty acid oxidation. Furthermore, CDY acts as a histone acetyltransferase, with strong preference for histone H4, a process required for the histone to proamine transition in spermatogenesis, consistent with the association with male infertility. Chromodomain Y-like protein (CDYL) is a related ubiquitous nuclear protein expressed at moderate levels in most tissues. The gene encoding for the CDYL protein localizes to chromosome 6p25.1.,Chromodomain Y-like protein 2
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分子量
- observerd band 56kDa
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基因ID
- 124359
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UniProt
- Q8N8U2
抗原
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