CHD1L 抗体 (Internal Region)
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北京 101111
Quick Overview for CHD1L 抗体 (Internal Region) (ABIN7217606)
抗原
See all CHD1L 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- CHD1L Polyclonal Antibody
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特异性
- CHD1L Polyclonal Antibody detects endogenous levels of CHD1L protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human CHD1L
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))
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别名
- CHD1L
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背景
- Rabbit Anti-CHD1L Polyclonal Antibody,CHD1L, ALC1, Chromodomain-helicase-DNA-binding protein 1-like, Amplified in liver cancer protein 1,CHD1L encodes a DNA helicase protein involved in DNA repair. The chromodomain-helicase-DNA-binding protein 1-like converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Several alternatively spliced transcripts variants have been described for this gene. CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like) is a Protein Coding gene. Diseases associated with CHD1L include fibrosarcoma of bone. Among its related pathways are Chromatin Regulation / Acetylation and DNA Double-Strand Break Repair. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and hydrolase activity. DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding.,Chromodomain-helicase-DNA-binding protein 1-like
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分子量
- observerd band 101kDa
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基因ID
- 9557
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UniProt
- Q86WJ1
抗原
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