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CBX5 抗体 (pSer92)

This 兔 多克隆 anti-CBX5 antibody specifically detects CBX5 in ELISA 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7220722
发货至: 中国
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Quick Overview for CBX5 抗体 (pSer92) (ABIN7220722)

抗原

See all CBX5 抗体
CBX5 (Chromobox Homolog 5 (CBX5))

适用

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宿主

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克隆类型

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多克隆

标记

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This CBX5 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    pSer92

    原理

    HP1α (phospho Ser92) Polyclonal Antibody

    特异性

    Phospho-HP1α (S92) Polyclonal Antibody detects endogenous levels of HP1α protein only when phosphorylated at S92.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human HP1alpha Phospho-Ser92

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    CBX5 (Chromobox Homolog 5 (CBX5))

    别名

    HP1alpha

    背景

    Rabbit Anti-HP1α (phospho Ser92) Polyclonal Antibody,CBX5, HP1A, Chromobox protein homolog 5, Antigen p25, Heterochromatin protein 1 homolog alpha, HP1 alpha,CBX5 encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The chromobox 5 is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.,Chromobox protein homolog 5

    基因ID

    23468

    UniProt

    P45973
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