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CBX3 抗体 (pSer93)

This 兔 多克隆 anti-CBX3 antibody specifically detects CBX3 in WB, ELISA 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7219318
发货至: 中国
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Quick Overview for CBX3 抗体 (pSer93) (ABIN7219318)

抗原

See all CBX3 抗体
CBX3 (Chromobox Homolog 3 (CBX3))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CBX3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    pSer93

    原理

    HP1γ (phospho Ser93) Polyclonal Antibody

    特异性

    Phospho-HP1γ (S93) Polyclonal Antibody detects endogenous levels of HP1γ protein only when phosphorylated at S93.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human HP1gamma Phospho-Ser93

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    CBX3 (Chromobox Homolog 3 (CBX3))

    别名

    HP1gamma

    背景

    Rabbit Anti-HP1γ (phospho Ser93) Polyclonal Antibody,CBX3, Chromobox protein homolog 3, HECH, Heterochromatin protein 1 homolog gamma, HP1 gamma, Modifier 2 protein,At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The chromobox 3 encoded by CBX3 binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.,Chromobox protein homolog 3

    分子量

    observerd band 24kDa

    基因ID

    11335, 653972

    UniProt

    Q13185
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