CBX3 抗体
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北京 101111
Quick Overview for CBX3 抗体 (ABIN7219316)
抗原
See all CBX3 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- HP1γ Polyclonal Antibody
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特异性
- HP1γ Polyclonal Antibody detects endogenous levels of HP1γ protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human HP1gamma around the non-phosphorylation site of S93
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CBX3 (Chromobox Homolog 3 (CBX3))
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别名
- HP1gamma
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背景
- Rabbit Anti-HP1γ Polyclonal Antibody,CBX3, Chromobox protein homolog 3, HECH, Heterochromatin protein 1 homolog gamma, HP1 gamma, Modifier 2 protein,At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The chromobox 3 encoded by CBX3 binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.,Chromobox protein homolog 3
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分子量
- observerd band 22kDa
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基因ID
- 11335
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UniProt
- Q13185
抗原
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