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CHRNA10 抗体 (AA 370-450)

This 兔 多克隆 anti-CHRNA10 antibody specifically detects CHRNA10 in WB 和 ELISA. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN7213448
发货至: 中国
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Quick Overview for CHRNA10 抗体 (AA 370-450) (ABIN7213448)

抗原

See all CHRNA10 抗体
CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

适用

  • 30
  • 12
  • 8
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 31
  • 2

克隆类型

  • 31
  • 2
多克隆

标记

  • 21
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CHRNA10 antibody is un-conjugated

应用范围

  • 23
  • 17
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  • 4
  • 3
  • 3
  • 2
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Western Blotting (WB), ELISA
  • 抗原表位

    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 370-450

    原理

    AChRα10 Polyclonal Antibody

    特异性

    AChRα10 Polyclonal Antibody detects endogenous levels of AChRα10 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the C-terminal region of human AChRalpha10 at AA range: 370-450

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

    别名

    AChRalpha10

    背景

    Rabbit Anti-AChRα10 Polyclonal Antibody,CHRNA10, NACHRA10, Neuronal acetylcholine receptor subunit alpha-10, Nicotinic acetylcholine receptor subunit alpha-10, NACHR alpha-10,Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters. Two important members of this family are the nicotinic acetylcholine and glutamate receptors, both of which are composed of five homologous subunits forming a transmembrane aqueous pore. These transmembrane receptors change conformation in response to their cognate neurotransmitter. Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system. The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, an enzyme that rapidly hydrolyzes acetylcholine. AChRα10, also known as CHRNA10, is a 450 amino acid multi-pass membrane protein expressed in inner-ear tissue, tonsil, immortalized B-cells, cultured T-cells and peripheral blood lymphocytes. AChRα10 forms a hetero-oligomeric channels in conjunction with AChRα9 and is considered an ionotropic receptor with a probable role in the modulation of auditory stimuli.,Neuronal acetylcholine receptor subunit alpha-10

    基因ID

    57053

    UniProt

    Q9GZZ6

    途径

    Sensory Perception of Sound, Synaptic Membrane
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