CHRNA10 抗体 (AA 370-450)
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Quick Overview for CHRNA10 抗体 (AA 370-450) (ABIN7213448)
抗原
See all CHRNA10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 370-450
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原理
- AChRα10 Polyclonal Antibody
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特异性
- AChRα10 Polyclonal Antibody detects endogenous levels of AChRα10 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human AChRalpha10 at AA range: 370-450
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))
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别名
- AChRalpha10
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背景
- Rabbit Anti-AChRα10 Polyclonal Antibody,CHRNA10, NACHRA10, Neuronal acetylcholine receptor subunit alpha-10, Nicotinic acetylcholine receptor subunit alpha-10, NACHR alpha-10,Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters. Two important members of this family are the nicotinic acetylcholine and glutamate receptors, both of which are composed of five homologous subunits forming a transmembrane aqueous pore. These transmembrane receptors change conformation in response to their cognate neurotransmitter. Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system. The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, an enzyme that rapidly hydrolyzes acetylcholine. AChRα10, also known as CHRNA10, is a 450 amino acid multi-pass membrane protein expressed in inner-ear tissue, tonsil, immortalized B-cells, cultured T-cells and peripheral blood lymphocytes. AChRα10 forms a hetero-oligomeric channels in conjunction with AChRα9 and is considered an ionotropic receptor with a probable role in the modulation of auditory stimuli.,Neuronal acetylcholine receptor subunit alpha-10
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基因ID
- 57053
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UniProt
- Q9GZZ6
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途径
- Sensory Perception of Sound, Synaptic Membrane
抗原
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