CCBP2 抗体 (AA 310-390)
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Quick Overview for CCBP2 抗体 (AA 310-390) (ABIN7214180)
抗原
See all CCBP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 310-390
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原理
- Rabbit Anti-Chemokine Receptor D6 Polyclonal Antibody
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特异性
- Chemokine Receptor D6 Polyclonal Antibody detects endogenous levels of Chemokine Receptor D6 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the C-terminal region of human Chemokine Receptor D6 at AA range: 310-390
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- CCBP2 (Chemokine Binding Protein 2 (CCBP2))
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别名
- Chemokine Receptor D6
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背景
- CCBP2, CCR10, CMKBR9, Chemokine-binding protein 2, C-C chemokine receptor D6, Chemokine receptor CCR-10, Chemokine receptor CCR-9, Chemokine-binding protein D6CCBP2 encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. CCBP2 is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members, however, its specific function remains unknown. CCBP2 is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.
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分子量
- 34kD
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基因ID
- 1238
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UniProt
- O00590
抗原
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