CXCR4 抗体 (pSer339)
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Quick Overview for CXCR4 抗体 (pSer339) (ABIN7225028)
抗原
See all CXCR4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer339
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原理
- Fusin (phospho Ser339) Polyclonal Antibody
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特异性
- Phospho-Fusin (S339) Polyclonal Antibody detects endogenous levels of Fusin protein only when phosphorylated at S339.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Fusin Phospho-Ser339
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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别名
- Fusin
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背景
- Rabbit Anti-Fusin (phospho Ser339) Polyclonal Antibody,CXCR4, C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, FB22, Fusin, HM89, LCR1, Leukocyte-derived seven transmembrane domain receptor, LESTR, NPYRL, Stromal cell-derived factor 1 receptor, SDF-1 receptor, CD antigen CD184,CXCR4 (C-X-C motif chemokine receptor 4) encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in CXCR4 have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.,C-X-C chemokine receptor type 4
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分子量
- observerd band 38kDa
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基因ID
- 7852
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UniProt
- P61073
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途径
- Regulation of Cell Size, CXCR4-mediated Signaling Events
抗原
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