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CCR7 抗体 (AA 140-220)

This 兔 多克隆 anti-CCR7 antibody specifically detects CCR7 in WB, ELISA 和 IF. The antibody is reactive with 人 和 猴 samples.
产品编号 ABIN7219462
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CCR7 抗体 (AA 140-220) (ABIN7219462)

抗原

See all CCR7 抗体
CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

适用

  • 129
  • 60
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  • 16
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  • 1
  • 1
人, 猴

宿主

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  • 38
  • 12
  • 5
  • 3
  • 1

克隆类型

  • 76
  • 67
  • 1
多克隆

标记

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  • 1
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  • 1
  • 1
  • 1
  • 1
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This CCR7 antibody is un-conjugated

应用范围

  • 66
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Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 16
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 140-220

    原理

    CKR-7 Polyclonal Antibody

    特异性

    CKR-7 Polyclonal Antibody detects endogenous levels of CKR-7 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human CKR-7 at AA range: 140-220

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

    别名

    CKR-7

    背景

    Rabbit Anti-CKR-7 Polyclonal Antibody,CCR7, CMKBR7, EBI1, EVI1, C-C chemokine receptor type 7, C-C CKR-7, CC-CKR-7, CCR-7, BLR2, CDw197, Epstein-Barr virus-induced G-protein coupled receptor 1, EBI1, EBV-induced G-protein coupled receptor 1, MIP-3 beta receptor, CD antigen CD19,The C-C motif chemokine receptor 7 encoded by CCR7 is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.,C-C chemokine receptor type 7

    分子量

    observerd band 43kDa

    基因ID

    1236

    UniProt

    P32248

    途径

    Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
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