CBLN2 抗体 (AA 130-210)
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北京 101111
Quick Overview for CBLN2 抗体 (AA 130-210) (ABIN7214156)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 130-210
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原理
- Cerebellin 2 Polyclonal Antibody
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特异性
- Cerebellin 2 Polyclonal Antibody detects endogenous levels of Cerebellin 2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human Cerebellin 2 at AA range: 130-210
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亚型
- IgG
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anti-Cerebellin 2 Precursor (CBLN2) (C-Term) antibody
CBLN2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cerebellin 2 Precursor (CBLN2) (N-Term) antibodyCBLN2 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cerebellin 2 Precursor (CBLN2) (C-Term) antibodyCBLN2 适用: 人, 大鼠, 小鼠, 猴 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cerebellin 2 Precursor (CBLN2) (AA 179-207), (C-Term) antibodyCBLN2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB29841 unconjugated
anti-Cerebellin 2 Precursor (CBLN2) (AA 186-215), (C-Term) antibodyCBLN2 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CBLN2 (Cerebellin 2 Precursor (CBLN2))
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别名
- Cerebellin 2
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背景
- Rabbit Anti-Cerebellin 2 Polyclonal Antibody,CBLN2, Cerebellin-2,Cerebellin (CER), which was originally isolated from rat cerebellum, is a hexadecapeptide derived from a larger precursor Cerebellin 1, also designated precerebellin 1 or Cbln1. Four propeptides, Cerebellin 1, Cerebellin 2 (Cbln2), Cerebellin 3 (Cbln3), and Cerebellin 4 (Cbln4), comprise the precerebellin subfamily within the C1q protein family. Cerebellin family members act as transneuronal regulators of synapse development and synaptic plasticity in various brain regions. CER and it metabolite des-Ser1-cerebellin are also expressed in several extra-cerebellar tissues, including adrenal gland. Cerebellin 1, 2 and 3 assemble into homomeric and heteromeric complexes, thereby influencing each other's degradation and secretion. Cerebellin 3 is not able to form homomeric complexes, and can only be secreted upon forming a heteromeric complex with Cerebellin 1. Decreased concentrations of CER has been found in the brain of patients with olivopontocerebellar atrophy (OPCA) and Shy-Drager syndrome, suggesting a role for CER in the pathology of these diseases.,Cerebellin-2
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分子量
- observerd band 24kDa
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基因ID
- 147381
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UniProt
- Q8IUK8
抗原
-
