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CERKL 抗体 (AA 310-390)

This 兔 多克隆 antibody specifically detects CERKL in ELISA, WB 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7214160
发货至: 中国
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Quick Overview for CERKL 抗体 (AA 310-390) (ABIN7214160)

抗原

See all CERKL 抗体
CERKL (Ceramide Kinase-Like (CERKL))

适用

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宿主

  • 23

克隆类型

  • 23
多克隆

标记

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This CERKL antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 310-390

    原理

    CERKL Polyclonal Antibody

    特异性

    CERKL Polyclonal Antibody detects endogenous levels of CERKL protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human CERKL at AA range: 310-390

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    CERKL (Ceramide Kinase-Like (CERKL))

    别名

    CERKL

    背景

    Rabbit Anti-CERKL Polyclonal Antibody,CERKL, Ceramide kinase-like protein,CERKL was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. CERKL encodes a protein (ceramide kinase like) with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.,Ceramide kinase-like protein

    分子量

    observerd band 63kDa

    基因ID

    375298

    UniProt

    Q49MI3
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