CEP95 抗体 (AA 560-640)
Quick Overview for CEP95 抗体 (AA 560-640) (ABIN7214026)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 560-640
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原理
- CCDC45 Polyclonal Antibody
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特异性
- CCDC45 Polyclonal Antibody detects endogenous levels of CCDC45 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human CCDC45 at AA range: 560-640
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亚型
- IgG
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anti-Centrosomal Protein 95kDa (CEP95) (AA 582-821) antibody
CEP95 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 95kDa (CEP95) (Internal Region) antibodyCEP95 适用: 人, 小鼠, 大鼠 ELISA, WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 95kDa (CEP95) (Internal Region) antibodyCEP95 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CEP95 (Centrosomal Protein 95kDa (CEP95))
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别名
- CCDC45
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背景
- Rabbit Anti-CCDC45 Polyclonal Antibody,CEP95, CCDC45, CEP45, Centrosomal protein of 95 kDa, Coiled-coil domain-containing protein 45,The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC45 (coiled-coil domain containing 45) is a 821 amino acid protein encoded by a gene that maps to human chromosome 17q23.3. Chromosome 17 comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.,Centrosomal protein of 95 kDa
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分子量
- observerd band 95kDa
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基因ID
- 90799
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UniProt
- Q96GE4
抗原
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