CEP55 抗体 (AA 50-130)
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Quick Overview for CEP55 抗体 (AA 50-130) (ABIN7214148)
抗原
See all CEP55 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-130
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原理
- CEP55 Polyclonal Antibody
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特异性
- CEP55 Polyclonal Antibody detects endogenous levels of CEP55 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human CEP55 at AA range: 50-130
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CEP55 (Centrosomal Protein 55kDa (CEP55))
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别名
- CEP55
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背景
- Rabbit Anti-CEP55 Polyclonal Antibody,CEP55, C10orf3, URCC6, Centrosomal protein of 55 kDa, Cep55, Up-regulated in colon cancer 6,CEP55 (Centrosomal protein of 55 kDa), also known as URCC6 (Up-regulated in colon cancer 6), is a 464 amino acid protein that localizes to the centrosome during interphase and may be found throughout the cell during mitosis. Widely expressed with highest expression in testis and lower expression in thymus, bone marrow, placenta, fetal heart, digestive tract and several carcinomas, CEP55 exists as a homodimer that interacts with centrosome components and is involved in mitotic exit and cytokinesis. Human CEP55 undergoes several phosphorylation events throughout the cell cycle, most of which are necessary for proper CEP55 function. Mutations or defects in the gene encoding CEP55 result in a failure to exit mitosis and may be associated with tumor progression. Two isoforms of CEP55 are expressed due to alternative splicing events.,Centrosomal protein of 55 kDa
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分子量
- observerd band 54kDa
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基因ID
- 55165
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UniProt
- Q53EZ4
抗原
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