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CENPJ 抗体 (AA 510-590)

This 兔 多克隆 anti-CENPJ antibody specifically detects CENPJ in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7227832
发货至: 中国
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Quick Overview for CENPJ 抗体 (AA 510-590) (ABIN7227832)

抗原

See all CENPJ 抗体
CENPJ (Centromere Protein J (CENPJ))

适用

  • 27
  • 5
  • 1
人, 小鼠

宿主

  • 23
  • 6

克隆类型

  • 26
  • 3
多克隆

标记

  • 19
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CENPJ antibody is un-conjugated

应用范围

  • 17
  • 12
  • 7
  • 6
  • 5
  • 5
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 510-590

    原理

    CENPJ Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of CENPJ protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human CENPJ protein at AA range: 510-590

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    CENPJ (Centromere Protein J (CENPJ))

    别名

    CENPJ

    背景

    Rabbit Anti-CENPJ Polyclonal Antibody,Centromere protein J, CENP-J, Centrosomal P4.1-associated protein, LAG-3-associated protein, LYST-interacting protein 1,CENPJ (Centromere Protein J) encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in CENPJ are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and cognitive disability. Alternatively spliced transcript variants have been found for CENPJ.,CENPJ

    分子量

    observerd band 147kDa

    基因ID

    55835

    UniProt

    Q9HC77

    途径

    M Phase
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