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CENPA 抗体

The 兔 多克隆 anti-CENPA antibody is suitable to detect CENPA in samples from 人. It has been validated for ELISA, IF 和 IHC (p).
产品编号 ABIN7219064
发货至: 中国
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Quick Overview for CENPA 抗体 (ABIN7219064)

抗原

See all CENPA 抗体
CENPA (Centromere Protein A (CENPA))

适用

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宿主

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克隆类型

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多克隆

标记

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This CENPA antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 原理

    CENP-A Polyclonal Antibody

    特异性

    CENP-A Polyclonal Antibody detects endogenous levels of CENP-A protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human CENP-A around the non-phosphorylation site of S7

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    CENPA (Centromere Protein A (CENPA))

    别名

    CENP-A

    背景

    Rabbit Anti-CENP-A Polyclonal Antibody,CENPA, Histone H3-like centromeric protein A, Centromere autoantigen A, Centromere protein A, CENP-A,Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,Histone H3-like centromeric protein A

    基因ID

    1058

    UniProt

    P49450

    途径

    Chromatin Binding, Maintenance of Protein Location
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