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CDCA3 抗体 (AA 190-270)

This anti-CDCA3 antibody is a 兔 多克隆 antibody detecting CDCA3 in WB, ELISA, IF 和 IHC (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7214118
发货至: 中国
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Quick Overview for CDCA3 抗体 (AA 190-270) (ABIN7214118)

抗原

See all CDCA3 抗体
CDCA3 (Cell Division Cycle Associated 3 (CDCA3))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This CDCA3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 190-270

    原理

    CdcA3 Polyclonal Antibody

    特异性

    CdcA3 Polyclonal Antibody detects endogenous levels of CdcA3 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the C-terminal region of human CdcA3 at AA range: 190-270

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    CDCA3 (Cell Division Cycle Associated 3 (CDCA3))

    别名

    CdcA3

    背景

    Rabbit Anti-CdcA3 Polyclonal Antibody,CDCA3, C8, GRCC8, TOME1, Cell division cycle-associated protein 3, Gene-rich cluster protein C8, Trigger of mitotic entry protein 1, TOME-1,Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by the proteolysis of cyclins. The cell division control (Cdc) genes are required at various points in the cell cycle. CdcA3 (Cell division cycle-associated protein 3), also known as TOME1 (Trigger of mitotic entry protein 1) and GRCC8 (Gene-rich cluster protein C8), is a 268 amino acid cytoplasmic protein that is required for entry into mitosis. By participating with E3 ligase complexes, CdcA3 is involved in ubiquination and degradation of the mitosis-inhibitory kinase Wee 1, leading to the dephosphorylation of Cdc2 in the late G2 phase. CdcA3 itself is targeted for destruction by anaphase promoting complex (APC) in the G1 phase of the cell cycle, then allowing for Wee 1 accumulation during interphase.,Cell division cycle-associated protein 3

    分子量

    observerd band 28kDa

    基因ID

    83461

    UniProt

    Q99618
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