CCAR1 抗体 (AA 840-920)
Quick Overview for CCAR1 抗体 (AA 840-920) (ABIN7227630)
抗原
See all CCAR1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 840-920
-
原理
- CCAR1 Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of CCAR1 protein
-
纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
-
免疫原
- Synthesized peptide derived from part region of human CCAR1 protein at AA range: 840-920
-
亚型
- IgG
-
-
anti-Cell Division Cycle and Apoptosis Regulator 1 (CCAR1) (AA 1-200) antibody
CCAR1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle and Apoptosis Regulator 1 (CCAR1) (AA 1-200) antibodyCCAR1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle and Apoptosis Regulator 1 (CCAR1) antibodyCCAR1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle and Apoptosis Regulator 1 (CCAR1) (Internal Region) antibodyVerified CCAR1 适用: 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Cell Division Cycle and Apoptosis Regulator 1 (CCAR1) antibodyCCAR1 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))
-
别名
- CCAR1
-
背景
- Rabbit Anti-CCAR1 Polyclonal Antibody,Cell division cycle and apoptosis regulator protein 1, Cell cycle and apoptosis regulatory protein 1, CARP-1, Death inducer with SAP domain,Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation. May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation. In association with CALCOCO1 enhances GATA1- and MED1-mediated transcriptional activation from the gamma-globin promoter during erythroid differentiation of K562 erythroleukemia cells. Can act as a both a coactivator and corepressor of AR-mediated transcription. Contributes to chromatin looping and AR transcription complex assembly by stabilizing AR-GATA2 association on chromatin and facilitating MED1 and RNA polymerase II recruitment to AR-binding sites. May play an important role in the growth and tumorigenesis of prostate cancer cells.,CCAR1
-
分子量
- observerd band 126kDa
-
基因ID
- 55749
-
UniProt
- Q8IX12
抗原
-
