CADM1 抗体 (AA 370-450)
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Quick Overview for CADM1 抗体 (AA 370-450) (ABIN7217400)
抗原
See all CADM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 370-450
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原理
- TSLC1 Polyclonal Antibody
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特异性
- TSLC1 Polyclonal Antibody detects endogenous levels of TSLC1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human TSLC1 at AA range: 370-450
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亚型
- IgG
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anti-Cell Adhesion Molecule 1 (CADM1) (AA 151-250) antibody
CADM1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (AA 148-163), (Extracellular) antibodyCADM1 适用: 小鼠 WB, IHC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (AA 365-442) antibodyCADM1 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (AA 65-160) antibodyCADM1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (Internal Region) antibodyCADM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (AA 45-344) antibodyCADM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (C-Term) antibodyCADM1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (C-Term) antibodyCADM1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (AA 27-292) antibodyCADM1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Cell Adhesion Molecule 1 (CADM1) (AA 45-344) antibodyCADM1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CADM1 (Cell Adhesion Molecule 1 (CADM1))
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别名
- TSLC1
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背景
- Rabbit Anti-TSLC1 Polyclonal Antibody,CADM1, IGSF4, IGSF4A, NECL2, SYNCAM, TSLC1, Cell adhesion molecule 1, Immunoglobulin superfamily member 4, IgSF4, Nectin-like protein 2, NECL-2, Spermatogenic immunoglobulin superfamily, SgIgSF, Synaptic cell adhesion molecule, SynCAM, Tumo,CADM1 (Cell Adhesion Molecule 1) is a Protein Coding gene. Diseases associated with CADM1 include asthenopia and lung cancer. Among its related pathways are Cell junction organization and Cell adhesion molecules (CAMs). Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and PDZ domain binding. An important paralog of this gene is CADM3. Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca(2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly (By similarity). May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.,Cell adhesion molecule 1
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分子量
- observerd band 49kDa
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基因ID
- 23705
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UniProt
- Q9BY67
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Activated T Cell Proliferation
抗原
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