Cdc14A Phosphatase (Internal Region) 抗体
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北京 101111
Quick Overview for Cdc14A Phosphatase (Internal Region) 抗体 (ABIN7225542)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- Rabbit Anti-Cdc14a phosphatase Polyclonal Antibody
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特异性
- Cdc14a phosphatase Polyclonal Antibody detects endogenous levels of Cdc14a phosphatase protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the Internal region of human Cdc14a phosphatase
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- Cdc14A Phosphatase
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背景
- CDC14A, Dual specificity protein phosphatase CDC14A, CDC14 cell division cycle 14 homolog AThe protein encoded by CDC14A (cell division cycle 14A) is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of CDC14A results in several transcript variants encoding distinct isoforms.
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分子量
- 66kD
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基因ID
- 8556
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UniProt
- Q9UNH5
抗原
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